Trazodone: The Go-To Sleep Aid

Trazodone is an older antidepressant that was originally developed to treat depression. Today, it’s rarely used for that purpose. Instead, it has become one of the most commonly prescribed medications for sleep. Both psychiatric specialists and primary care providers often prescribe trazodone for insomnia because of its sedating effects.

How Trazodone Works

When used for sleep, trazodone is usually prescribed at much lower doses than the doses used for treating depression. It works by modulating brain chemicals such as serotonin and histamine, which play key roles in regulating sleep. By affecting these pathways, trazodone can help promote relaxation and make it easier to fall and stay asleep.

Effect on Sleep Quality

Studies have shown that trazodone can improve both the depth and quality of sleep. Many patients report waking up feeling more refreshed compared to other sleep aids, which sometimes only increase sleep duration without improving restorative sleep.

Common Side Effects

Some of the more common side effects of trazodone include drowsiness, dry mouth, dizziness, headache, and grogginess the following morning. These effects are often dose dependent, and starting at a lower dose can help minimize them.

Serious Side Effects

Although uncommon, trazodone can cause more serious side effects. These include low blood pressure (especially when standing up), irregular heart rhythms, and in rare cases, priapism (a prolonged and painful erection). Anyone experiencing severe or unusual symptoms should seek medical attention right away.

Key Takeaways

Trazodone can be an effective, non-habit-forming option for people struggling with sleep. It’s generally well tolerated, especially at the low doses used for insomnia. However, it’s still a prescription medication that affects brain chemistry, so it should be used under the guidance of a qualified healthcare provider. If you experience persistent side effects or the medication doesn’t work as expected, talk with your provider to explore alternative options.